Formulation and Characterization of Metformin-Loaded Ethosomes for Topical Application to Experimentally Induced Skin Cancer in Mice

• Main Authors: Ibrahim A. Mousa (Author), Taha M. Hammady (Author), Shadeed Gad (Author), Sawsan A. Zaitone (Author), Mohamed El-Sherbiny (Author), Ossama M. Sayed (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To achieve the best treatment of skin cancer, drug penetration inside the deepest layers of the skin is an important scientific interest. We designed an ethosome formulation that serves as a carrier for metformin and measured the in vitro skin permeation. We also aimed to measure the antitumor activ...