Nrf2 Deficiency Accelerates IL-17-Dependent Neutrophilic Airway Inflammation in Asthmatic Mice

• Egile Nagusiak: Kenya Kuramoto (Egilea), Yuko Morishima (Egilea), Kazufumi Yoshida (Egilea), Satoshi Ano (Egilea), Kai Kawashima (Egilea), Yuki Yabuuchi (Egilea), Chio Sakai (Egilea), Sosuke Matsumura (Egilea), Kengo Nishino (Egilea), Kai Yazaki (Egilea), Masashi Matsuyama (Egilea), Takumi Kiwamoto (Egilea), Yukio Ishii (Egilea), Nobuyuki Hizawa (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2024-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Asthma is a heterogeneous disease that can be broadly classified into type 2, which is primarily steroid-sensitive and eosinophilic, and non-type 2, which is primarily steroid-resistant and neutrophilic. While the mechanisms leading to the development of molecular-targeted therapies for type 2 asthm...