Preparation, characterization and antitumor activity evaluation of apigenin nanoparticles by the liquid antisolvent precipitation technique

• Main Authors: Weiwei Wu (Author), Yuangang Zu (Author), Li Wang (Author), Lingling Wang (Author), Huimei Wang (Author), Yuanyuan Li (Author), Mingfang Wu (Author), Xiuhua Zhao (Author), Yujie Fu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present work aimed to apply the liquid antisolvent precipitation (LAP) method for preparing the apigenin nanoparticles and thereby improving the solubility and bioavailability of apigenin. The different experimental parameters on particle size were optimized through central composite design (CCD...