Hollow Alginate-Poly-L-Lysine-Alginate Microspheres Promoted an Epithelial-Mesenchymal Transition in Human Colon Adenocarcinoma Cells

• Main Authors: Shirin Saberianpour (Author), Arezoo Rezaie Nezhad Zamani (Author), Abbas Karimi (Author), Mahdi Ahmadi (Author), Neda Khatami (Author), Ayda Pouyafar (Author), Reza Rahbarghazi (Author), Mohammad Nouri (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Today, there is an urgent need to develop a three-dimentional culture systems mimicking native in vivo condition in order to screen potency of drugs and possibly any genetic alterations in tumor cells. Due to the existence of limitations in animal models, the development of three dimensiona...