NF-κB mediated regulation of tumor cell proliferation in hypoxic microenvironment
Hypoxia is caused by a cancer-promoting milieu characterized by persistent inflammation. NF-κB and HIF-1α are critical participants in this transition. Tumor development and maintenance are aided by NF-κB, while cellular proliferation and adaptability to angiogenic signals are aided by HIF-1α. Proly...
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Frontiers Media S.A.,
2023-02-01T00:00:00Z.
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