Targeted Therapy of Hepatocellular Carcinoma Using Gemcitabine-Incorporated GPC3 Aptamer

• Main Authors: Jun Young Park (Author), Ju Ri Chae (Author), Ye Lim Cho (Author), Youndong Kim (Author), Dasom Lee (Author), Jeong Kyun Lee (Author), Won Jun Kang (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2020-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Hepatocellular carcinoma (HCC) is the most common malignancy of the liver, which can progress rapidly and has a poor prognosis. Glypican-3 (GPC3) has been proposed to be an important diagnostic biomarker and therapeutic target for HCC. Aptamers have emerged as promising drug delivery vehicles becaus...