Adipocyte-specific ablation of the Ca2+ pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissue

• मुख्य लेखकों: Marco Bauzá-Thorbrügge (लेखक), Elin Banke (लेखक), Belén Chanclón (लेखक), Eduard Peris (लेखक), Yanling Wu (लेखक), Saliha Musovic (लेखक), Cecilia Jönsson (लेखक), Peter Strålfors (लेखक), Patrik Rorsman (लेखक), Charlotta S. Olofsson (लेखक), Ingrid Wernstedt Asterholm (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2022-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) transports Ca2+ from the cytosol into the endoplasmic retitculum (ER) and is essential for appropriate regulation of intracellular Ca2+ homeostasis. The objective of this study was to test the hypothesis that SERCA pumps are involved in the...