Development and Evaluation of Novel Metformin Derivative Metformin Threonate for Brain Ischemia Treatment

• Glavni autori: Gufang Zhang (Autor), Shuangshuang Chen (Autor), Jia Jia (Autor), Chun Liu (Autor), Weipeng Wang (Autor), Hongjian Zhang (Autor), Xuechu Zhen (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Epidemiologic data reveal that diabetes patients taking metformin exhibit lower incidence of stroke and better functional outcomes during post-stroke neurologic recovery. We previously demonstrated that chronic post-ischemic administration of metformin improved functional recovery in experimental ce...