Neuroinflammation alters GABAergic neurotransmission in hyperammonemia and hepatic encephalopathy, leading to motor incoordination. Mechanisms and therapeutic implications

• मुख्य लेखकों: Marta Llansola (लेखक), Yaiza M. Arenas (लेखक), María Sancho-Alonso (लेखक), Gergana Mincheva (लेखक), Andrea Palomares-Rodriguez (लेखक), Magnus Doverskog (लेखक), Paula Izquierdo-Altarejos (लेखक), Vicente Felipo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Enhanced GABAergic neurotransmission contributes to impairment of motor coordination and gait and of cognitive function in different pathologies, including hyperammonemia and hepatic encephalopathy. Neuroinflammation is a main contributor to enhancement of GABAergic neurotransmission through increas...