Neuroinflammation alters GABAergic neurotransmission in hyperammonemia and hepatic encephalopathy, leading to motor incoordination. Mechanisms and therapeutic implications

• Główni autorzy: Marta Llansola (Autor), Yaiza M. Arenas (Autor), María Sancho-Alonso (Autor), Gergana Mincheva (Autor), Andrea Palomares-Rodriguez (Autor), Magnus Doverskog (Autor), Paula Izquierdo-Altarejos (Autor), Vicente Felipo (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Enhanced GABAergic neurotransmission contributes to impairment of motor coordination and gait and of cognitive function in different pathologies, including hyperammonemia and hepatic encephalopathy. Neuroinflammation is a main contributor to enhancement of GABAergic neurotransmission through increas...