Synthesis and in vitro anti-HIV-1 evaluation of some N-arylsulfonyl-3-formylindoles

• Main Authors: Zhiping Che (Author), Yuee Tian (Author), Shengming Liu (Author), Mei Hu (Author), Genqiang Chen (Author)
• 格式: 圖書
• 出版: Universidade de São Paulo, 2018-11-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

As our ongoing work on research of anti-HIV-1 inhibitors, fifteen N-arylsulfonyl-3-formylindoles (3a-o) were designed and prepared through two step synthetic route. Firstly, 3-formylindoles (2a-c) were synthesized via the Vilsmeier-Haack reaction. Subsequently, treatment of 2a-c with the appropriate...