Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis

• मुख्य लेखकों: Kristin Eden (लेखक), Daniel E. Rothschild (लेखक), Dylan K. McDaniel (लेखक), Bettina Heid (लेखक), Irving C. Allen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2017-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Eosinophilic esophagitis (EoE) is an allergic disease of the esophagus driven by T cell and eosinophil responses to dietary allergens, resulting in chronic mucosal inflammation. Few spontaneous animal models of esophageal eosinophilia exist, with most studies relying on artificial sensitization proc...