Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis

• Glavni autori: Kristin Eden (Autor), Daniel E. Rothschild (Autor), Dylan K. McDaniel (Autor), Bettina Heid (Autor), Irving C. Allen (Autor)
• Format: Knjiga
• Izdano: The Company of Biologists, 2017-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Eosinophilic esophagitis (EoE) is an allergic disease of the esophagus driven by T cell and eosinophil responses to dietary allergens, resulting in chronic mucosal inflammation. Few spontaneous animal models of esophageal eosinophilia exist, with most studies relying on artificial sensitization proc...