Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress

• Autors principals: Wen Chen (Autor), Chenzhou Wu (Autor), Yafei Chen (Autor), Yuhao Guo (Autor), Ling Qiu (Autor), Zhe Liu (Autor), Haibin Sun (Autor), Siyu Chen (Autor), Zijian An (Autor), Zhuoyuan Zhang (Autor), Yi Li (Autor), Longjiang Li (Autor)
• Format: Llibre
• Publicat: Nature Publishing Group, 2021-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract C18 ceramide plays an important role in the occurrence and development of oral squamous cell carcinoma. However, the function of ceramide synthase 1, a key enzyme in C18 ceramide synthesis, in oral squamous cell carcinoma is still unclear. The aim of our study was to investigate the relatio...