Differential Inotropic Effects of Endothelin-1, Angiotensin II, and Phenylephrine Induced by Crosstalk With cAMP-Mediated Signaling Process in Dog Ventricular Myocardium

• Váldodahkkit: Li Chu (Dahkki), Ikuo Norota (Dahkki), Shin-ichi Yomogida (Dahkki), Kuniaki Ishii (Dahkki), Masao Endoh (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2004-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Endothelin-1 (ET-1), angiotensin II (Ang II), and phenylephrine, an α2-adrenoceptor agonist, share the common signaling process, resulting in activation of Gq protein-coupled receptor (GqPCR) to activate the hydrolysis of phosphoinositide (PI). They do not elicit any inotropic effect in isolated dog...