A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis

• Hoofdauteurs: Soad A. Mohamad (Auteur), Mohamed A. Safwat (Auteur), Mahmoud Elrehany (Auteur), Sherif A. Maher (Auteur), Ahmed M. Badawi (Auteur), Heba F. Mansour (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Purpose The work aimed to develop a co-loaded loratadine and sulpiride nasal nanoemulsion for allergic rhinitis management. Methods Compatibility studies were conducted adopting differential scanning calorimetry and Fourier transform infrared spectroscopy. Nanoemulsion formulations were prepared usi...