Knockdown of NEK7 alleviates anterior cruciate ligament transection osteoarthritis (ACLT)-induced knee osteoarthritis in mice via inhibiting NLRP3 activation

Osteoarthritis is thought to be a NLRP3-related disease. NEK7 is an essential mediator for NLRP3 inflammasome activation. This study aimed to demonstrate whether NEK7 has regulatory roles in the pathogenesis of osteoarthritis. C57BL/6 mice were subjected to anterior cruciate ligament transection ost...

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Main Authors: Wei Sun (Author), Maoxing Yue (Author), Guangmin Xi (Author), Kai Wang (Author), Jiaming Sai (Author)
Format: Book
Published: Taylor & Francis Group, 2022-08-01T00:00:00Z.
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3rd Floor Main Library

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