Effects of Drug Physicochemical Properties on In-Situ Forming Implant Polymer Degradation and Drug Release Kinetics

• Main Authors: Jordan B. Joiner (Author), Alka Prasher (Author), Isabella C. Young (Author), Jessie Kim (Author), Roopali Shrivastava (Author), Panita Maturavongsadit (Author), Soumya Rahima Benhabbour (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In-situ forming implants (ISFIs) represent a simple, tunable, and biodegradable polymer-based platform for long-acting drug delivery. However, drugs with different physicochemical properties and physical states in the polymer-solvent system exhibit different drug release kinetics. Although a few lim...