Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells

• Main Authors: Muthu Ramkumar (Author), Srinivasagam Rajasankar (Author), Veerappan Venkatesh Gobi (Author), Chinnasamy Dhanalakshmi (Author), Thamilarasan Manivasagam (Author), Arokiasamy Justin Thenmozhi (Author), Musthafa Mohamed Essa (Author), Ameer Kalandar (Author), Ranganathan Chidambaram (Author)
• Format: Book
• Published: BMC, 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mitochondrial dysfunction and oxidative stress are the main toxic events leading to dopaminergic neuronal death in Parkinson's disease (PD) and identified as vital objective for therapeutic intercession. This study investigated the neuro-protective effects of the demethoxycu...