A small molecule inhibitor of Notch1 modulates stemness and suppresses breast cancer cell growth

• Päätekijät: Uttara Saran (Tekijä), Balaji Chandrasekaran (Tekijä), Ashish Tyagi (Tekijä), Vaibhav Shukla (Tekijä), Amandeep Singh (Tekijä), Arun K. Sharma (Tekijä), Chendil Damodaran (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Although breast cancer stem cells (BCSCs) are well characterized, molecularly targeting and eradicating this sub-population remains a challenge in the clinic. Recent studies have explored several signaling pathways that govern stem cell activation: We and others established that the Notch1 signaling...