Characteristics of Skin Deposition of Itraconazole Solubilized in Cream Formulation

• Autores principales: Hyeongmin Kim (Autor), Sukkyun Jung (Autor), Sooho Yeo (Autor), Dohyun Kim (Autor), Young Chae Na (Autor), Gyiae Yun (Autor), Jaehwi Lee (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2019-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Itraconazole (ITZ) is an anti-fungal agent generally used to treat cutaneous mycoses. For efficient delivery of ITZ to the skin tissues, an oil-in-water (O/W) cream formulation was developed. The O/W cream base was designed based on the solubility measurement of ITZ in various excipients. A physical...