The roles of protocadherin-7 in colorectal cancer cells on cell proliferation and its chemoresistance

• প্রধান লেখক: Zhibao Zheng (লেখক), Na Luan (লেখক), Kai Tu (লেখক), Feiyan Liu (লেখক), Jianwei Wang (লেখক), Jianguo Sun (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Despite the high mutation frequencies of KRAS, NRAS, and BRAF in colorectal cancer (CRC), there are no effective and reliable inhibitors for these biomarkers. Protocadherin-7 (PCDH7) is regarded as a potentially targetable surface molecule in cancer cells and plays an important role in their prolife...