Progranulin Improves Acute Lung Injury through Regulating the Differentiation of Regulatory T Cells and Interleukin-10 Immunomodulation to Promote Macrophage Polarization

Progranulin (PGRN), which plays an anti-inflammatory role in acute lung injury (ALI), is promising as a potential drug. Studies have shown that regulatory T cells (Tregs) and interleukin- (IL-) 10 can repress inflammation and alleviate tissue damage during ALI. In this study, we built a lipopolysacc...

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Bibliographic Details
Main Authors: Yan-qing Chen (Author), Chuan-jiang Wang (Author), Ke Xie (Author), Ming Lei (Author), Yu-sen Chai (Author), Fang Xu (Author), Shi-hui Lin (Author)
Format: Book
Published: Hindawi Limited, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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