SNP-SNP interactions dominate the genetic architecture of candidate genes associated with left ventricular mass in african-americans of the GENOA study

• Hlavní autoři: Mosley Thomas H (Autor), Chu Jian (Autor), Meyers Kristin J (Autor), Kardia Sharon LR (Autor)
• Médium: Kniha
• Vydáno: BMC, 2010-11-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Left ventricular mass (LVM) is a strong, independent predictor of heart disease incidence and mortality. LVM is a complex, quantitative trait with genetic and environmental risk factors. This research characterizes the genetic archit...