CAR-T cells: Early successes in blood cancer and challenges in solid tumors

• Main Authors: Hassan Dana (Author), Ghanbar Mahmoodi Chalbatani (Author), Seyed Amir Jalali (Author), Hamid Reza Mirzaei (Author), Stephan A. Grupp (Author), Eloah Rabello Suarez (Author), Catarina Rapôso (Author), Thomas J. Webster (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

New approaches to cancer immunotherapy have been developed, showing the ability to harness the immune system to treat and eliminate cancer. For many solid tumors, therapy with checkpoint inhibitors has shown promise. For hematologic malignancies, adoptive and engineered cell therapies are being wide...