Combination of Estradiol with Leukemia Inhibitory Factor Stimulates Granulosa Cells Differentiation into Oocyte-Like Cells

• Main Authors: Soudabe Yousefi (Author), Maryam Akbarzadeh (Author), Jafar Soleimanirad (Author), Kobra Hamdi (Author), Laya Farzadi (Author), Aalie Ghasemzadeh (Author), Mahdi Mahdipour (Author), Reza Rahbarghazi (Author), Mohammad Nouri (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Previous studies have documented that cumulus granulosa cells (GCs) can trans-differentiation into different non-ovarian cells, showing their multipotentiality to repopulate the injured cells in ovarian tissue. The current experiment is aimed to assess the differentiation capacity of human...