Role of the CaV1.2 distal carboxy terminus in the regulation of L-type current

• Main Authors: Felipe Arancibia (Author), Daniela De Giorgis (Author), Franco Medina (Author), Tamara Hermosilla (Author), Felipe Simon (Author), Diego Varela (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTL-type calcium channels are essential for the excitation-contraction coupling in cardiac muscle. The CaV1.2 channel is the most predominant isoform in the ventricle which consists of a multi-subunit membrane complex that includes the CaV1.2 pore-forming subunit and auxiliary subunits like Ca...