A mix & act liposomes of phospholipase A2-phosphatidylserine for acute brain detoxification by blood‒brain barrier selective-opening

• Main Authors: Zinan Zhang (Author), Wenbin Cao (Author), Huanchun Xing (Author), Shuai Guo (Author), Lijuan Huang (Author), Lin Wang (Author), Xin Sui (Author), Kui Lu (Author), Yuan Luo (Author), Yongan Wang (Author), Jun Yang (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the treatment of central nervous system disease, the blood-brain barrier (BBB) is a major obstruction to drug delivery that must be overcome. In this study, we propose a brain-targeted delivery strategy based on selective opening of the BBB. This strategy allows some simple bare nanoparticles to...