Erk5 Mediates TGFβ1-induced Loss of Phenotype and Function in Human Podocytes

• Main Authors: Irbaz Isaac Badshah (Author), Deborah L Baines (Author), Mark Edward Dockrell (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic nephropathy is one of the most common causes of renal impairment. Podocytes are specialised cells integral to normal kidney physiology, however in diabetes injury occurs leading to compromised function which is a critical factor in the development of the disease. TGFβ1 is known to play a ma...