A Single-Cell Atlas of the Substantia Nigra Reveals Therapeutic Effects of Icaritin in a Rat Model of Parkinson's Disease

• Main Authors: Hao Wu (Author), Zhen-Hua Zhang (Author), Ping Zhou (Author), Xin Sui (Author), Xi Liu (Author), Yi Sun (Author), Xin Zhao (Author), Xiao-Ping Pu (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Degeneration and death of dopaminergic neurons in the substantia nigra of the midbrain are the main pathological changes in Parkinson's disease (PD); however, the mechanism underlying the selective vulnerability of specific neuronal populations in PD remains unclear. Here, we used single-cell R...