A Single-Cell Atlas of the Substantia Nigra Reveals Therapeutic Effects of Icaritin in a Rat Model of Parkinson's Disease

• Hlavní autoři: Hao Wu (Autor), Zhen-Hua Zhang (Autor), Ping Zhou (Autor), Xin Sui (Autor), Xi Liu (Autor), Yi Sun (Autor), Xin Zhao (Autor), Xiao-Ping Pu (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2024-09-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Degeneration and death of dopaminergic neurons in the substantia nigra of the midbrain are the main pathological changes in Parkinson's disease (PD); however, the mechanism underlying the selective vulnerability of specific neuronal populations in PD remains unclear. Here, we used single-cell R...