New Approaches to Blockade of the Renin-Angiotensin-Aldosterone System: Characteristics and Usefulness of the Direct Renin Inhibitor Aliskiren

• Egile Nagusiak: Atsuhiro Ichihara (Egilea), Mariyo Sakoda (Egilea), Asako Kurauchi-Mito (Egilea), Tatsuya Narita (Egilea), Kenichiro Kinouchi (Egilea), Kanako Bokuda (Egilea), Hiroshi Itoh (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2010-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Since renin inhibition interferes with the first and rate-limiting steps in the renin-angiotensin system, the renin step is a very attractive target for lowering blood pressure and minimizing target-organ damage. The newly developed direct renin inhibitor aliskiren has several attractive characteris...