Loop-mediated Isothermal Amplification and nested PCR of the Internal Transcribed Spacer (ITS) for Histoplasma capsulatum detection.

• Main Authors: Matheus da Silva Zatti (Author), Thales Domingos Arantes (Author), José Alex Lourenço Fernandes (Author), Mônica Baumgardt Bay (Author), Eveline Pipolo Milan (Author), Georggia Fatima Silva Naliato (Author), Raquel Cordeiro Theodoro (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Histoplasmosis is a neglected disease that affects mainly immunocompromised patients, presenting a progressive dissemination pattern and a high mortality rate, mainly due to delayed diagnosis, caused by slow fungal growth in culture. Therefore, a fast, suitable and cos...