Sesquiterpene lactones-enriched fractions from Xanthium mongolicum Kitag alleviate RA by regulating M1 macrophage polarization via NF-κB and MAPK signaling pathway

• Main Authors: Jing Han (Author), Jingwen Wang (Author), Yicun Wang (Author), Zhiqi Zhu (Author), Siwang Zhang (Author), Bingrong Wu (Author), Mingsong Meng (Author), Jianning Zhao (Author), Dongsheng Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease, characterized by activated M1-like macrophage in the joint. Xanthium mongolicum Kitag (X. mongolicum) is a traditional medicinal plant that has long been used to treat RA and other immune diseases in China.Methods: Fractions of...