Hydrophobic binding peptide-conjugated hybrid lipid-mesoporous silica nanoparticles for effective chemo-photothermal therapy of pancreatic cancer

• Main Authors: Raj Kumar Thapa (Author), Hanh Thuy Nguyen (Author), Milan Gautam (Author), Aarajana Shrestha (Author), Eung Seok Lee (Author), Sae Kwang Ku (Author), Han-Gon Choi (Author), Chul Soon Yong (Author), Jong Oh Kim (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanoparticle-based drug delivery systems are designed to reach tumor sites based on their enhanced permeation and retention effects. However, a lack of interaction of these nanoparticles with cancer cells might lead to reduced uptake in the tumors, which might compromise the therapeutic efficacy of...