Angelicin improves osteoporosis in ovariectomized rats by reducing ROS production in osteoclasts through regulation of the KAT6A/Nrf2 signalling pathway

• Main Authors: Xiao-feng Liu (Author), Yi-tao Liao (Author), Jia-hao Shao (Author), Dan-dan He (Author), Zhi-hong Fan (Author), Ye-Nan Xu (Author), Chao Li (Author), Xian Zhang (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Angelicin, which is found in Psoralea, can help prevent osteoporosis by stopping osteoclast formation, although the precise mechanism remains unclear. Methods We evaluated the effect of angelicin on the oxidative stress level of osteoclasts using ovariectomized osteoporosis model...