Angelicin improves osteoporosis in ovariectomized rats by reducing ROS production in osteoclasts through regulation of the KAT6A/Nrf2 signalling pathway

• প্রধান লেখক: Xiao-feng Liu (লেখক), Yi-tao Liao (লেখক), Jia-hao Shao (লেখক), Dan-dan He (লেখক), Zhi-hong Fan (লেখক), Ye-Nan Xu (লেখক), Chao Li (লেখক), Xian Zhang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2024-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Angelicin, which is found in Psoralea, can help prevent osteoporosis by stopping osteoclast formation, although the precise mechanism remains unclear. Methods We evaluated the effect of angelicin on the oxidative stress level of osteoclasts using ovariectomized osteoporosis model...