Label-free quantitative proteomic analyses of mouse astrocytes provides insight into the host response mechanism at different developmental stages of Toxoplasma gondii.

• Main Authors: Huanhuan Xie (Author), Hang Sun (Author), Hongjie Dong (Author), Lisha Dai (Author), Haozhi Xu (Author), Lixin Zhang (Author), Qi Wang (Author), Junmei Zhang (Author), Guihua Zhao (Author), Chao Xu (Author), Kun Yin (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toxoplasma gondii (T. gondii) is an opportunistic parasite that can infect the central nervous system (CNS), causing severe toxoplasmosis and behavioral cognitive impairment. Mortality is high in immunocompromised individuals with toxoplasmosis, most commonly due to reactivation of infection in the...