Adoptive transfer of type 1 regulatory T cells suppressed the development of airway hyperresponsiveness in ovalbumin-induced airway inflammation model mice

• Main Authors: Masaya Matsuda (Author), Kana Doi (Author), Tatsuya Tsutsumi (Author), Miki Inaba (Author), Junpei Hamaguchi (Author), Tetsuya Terada (Author), Ryo Kawata (Author), Kazuyuki Kitatani (Author), Takeshi Nabe (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type 1 regulatory T (Tr1) cells are CD4+ T cells that produce a large amount of IL-10, an anti-inflammatory cytokine. However, it has not been fully elucidated whether Tr1 cells suppress allergic asthma. In this study, the effects of adoptive transfer of in vitro-induced Tr1 cells on allergic asthma...