Immune protection against Trypanosoma cruzi induced by TcVac4 in a canine model.

• मुख्य लेखकों: José E Aparicio-Burgos (लेखक), José A Zepeda-Escobar (लेखक), Roberto Montes de Oca-Jimenez (लेखक), José G Estrada-Franco (लेखक), Alberto Barbabosa-Pliego (लेखक), Laucel Ochoa-García (लेखक), Ricardo Alejandre-Aguilar (लेखक), Nancy Rivas (लेखक), Giovanna Peñuelas-Rivas (लेखक), Margarita Val-Arreola (लेखक), Shivali Gupta (लेखक), Felix Salazar-García (लेखक), Nisha J Garg (लेखक), Juan C Vázquez-Chagoyán (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2015-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Chagas disease, caused by Trypanosoma cruzi, is endemic in southern parts of the American continent. Herein, we have tested the protective efficacy of a DNA-prime/T. rangeli-boost (TcVac4) vaccine in a dog (Canis familiaris) model. Dogs were immunized with two-doses of DNA vaccine (pcDNA3.1 encoding...