Construction and Transfer of PEI-miRNA-126/210 Polyplex into Human Umbilical Vein Endothelial Cells with Investigation of Its Effect on Islets Survival and Function

• Main Authors: Fatemeh Sabet Sarvestani (Author), Ali-Mohammad Tamaddon (Author), Mohammad-Hosein Karimi (Author), Ramin Yaghoobi (Author), Bita Geramizadeh (Author), Mozhdeh Heydari (Author), Ismail H. Al-Abdullah (Author), Negar Azarpira (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Type 1 diabetes is an autoimmune disorder characterized by the loss of pancreatic islets. Islet allotransplantation is a potentially beneficial therapeutic approach for diabetes. Islets suffer a variety of cellular insults including ischemia and partial vascular loss during isolation, re...