Obesogenic Diet in Mice Leads to Inflammation and Oxidative Stress in the Mother in Association with Sex-Specific Changes in Fetal Development, Inflammatory Markers and Placental Transcriptome

• Main Authors: Alejandro A. Candia (Author), Samantha C. Lean (Author), Cindy X. W. Zhang (Author), Daniel R. McKeating (Author), Anna Cochrane (Author), Edina Gulacsi (Author), Emilio A. Herrera (Author), Bernardo J. Krause (Author), Amanda N. Sferruzzi-Perri (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Obesity during pregnancy is related to adverse maternal and neonatal outcomes. Factors involved in these outcomes may include increased maternal insulin resistance, inflammation, oxidative stress, and nutrient mishandling. The placenta is the primary determinant of fetal outcomes, and it...