Long-Circulating Hyaluronan-Based Nanohydrogels as Carriers of Hydrophobic Drugs

• Main Authors: Chiara Di Meo (Author), Mayte Martínez-Martínez (Author), Tommasina Coviello (Author), Marival Bermejo (Author), Virginia Merino (Author), Isabel Gonzalez-Alvarez (Author), Marta Gonzalez-Alvarez (Author), Pietro Matricardi (Author)
• Format: Book
• Published: MDPI AG, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanohydrogels based on natural polymers, such as polysaccharides, are gaining interest as vehicles for therapeutic agents, as they can modify the pharmacokinetics and pharmacodynamics of the carried drugs. In this work, hyaluronan-riboflavin nanohydrogels were tested in vivo in healthy rats highligh...