An Artificial Neural Network Approach to Predict the Effects of Formulation and Process Variables on Prednisone Release from a Multipartite System

• Main Authors: Arthur Manda (Author), Roderick B. Walker (Author), Sandile M. M. Khamanga (Author)
• Formato: Libro
• Publicado: MDPI AG, 2019-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The impact of formulation and process variables on the in-vitro release of prednisone from a multiple-unit pellet system was investigated. Box-Behnken Response Surface Methodology (RSM) was used to generate multivariate experiments. The extrusion-spheronization method was used to produce pellets and...