Functional reorganization of monoamine transport systems during villous trophoblast differentiation: evidence of distinct differences between primary human trophoblasts and BeWo cells

• Main Authors: Veronika Vachalova (Author), Rona Karahoda (Author), Martina Ottaviani (Author), Kasin Yadunandam Anandam (Author), Cilia Abad (Author), Christiane Albrecht (Author), Frantisek Staud (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Three primary monoamines-serotonin, norepinephrine, and dopamine-play major roles in the placenta-fetal brain axis. Analogously to the brain, the placenta has transport mechanisms that actively take up these monoamines into trophoblast cells. These transporters are known to play...