Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway

• প্রধান লেখক: Xianzhi Li (লেখক), Xiaojun Zhou (লেখক), Xigao Liu (লেখক), Xiaoyun Li (লেখক), Xianzhou Jiang (লেখক), Benkang Shi (লেখক), Shuo Wang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2022-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Acute kidney injury (AKI) is still a critical problem in clinical practice, with a heavy burden for national health system around the world. It is notable that sepsis is the predominant cause of AKI for patients in the intensive care unit and the mortality remains considerably hi...