Substance P Antagonist Aprepitant Shows no Additive Effect Compared with Standardized Topical Treatment Alone in Patients with Atopic Dermatitis

• Main Authors: Louise Lönndahl (Author), Mikael Holst (Author), Maria Bradley (Author), Hassan Killasli (Author), Johan Heilborn (Author), Martin A. Hall (Author), Elvar Theodorsson (Author), Jadwiga Holmberg (Author), Klas Nordlind (Author)
• Format: Book
• Published: Medical Journals Sweden, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atopic dermatitis (AD) is a chronic, itchy, inflammatory skin disorder that may worsen due to stress and anxiety. Tachykinins have been suggested to be involved in the inflammation in AD, as well as pruritus. Aprepitant is a NK-1 receptor antagonist. This open randomized trial evaluated the effect o...