Experience and pharmacokinetics of Levetiracetam in Korean neonates with neonatal seizures

• Main Authors: Jae Won Shin (Author), Yun Seob Jung (Author), Kyungsoo Park (Author), Soon Min Lee (Author), Ho Seon Eun (Author), Min Soo Park (Author), Kook In Park (Author), Ran Namgung (Author)
• Format: Book
• Published: Korean Pediatric Society, 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeThe aims of this study were to evaluate the safety and pharmacokinetics of levetiracetam (LEV) in neonates with seizures and to establish a population pharmacokinetics (PPK) model by using the software NONMEM.MethodsA retrospective analysis of 18 neonatal patients with seizures, who were trea...