Perturbed development of cranial neural crest cells in association with reduced sonic hedgehog signaling underlies the pathogenesis of retinoic-acid-induced cleft palate

• Главные авторы: Qi Wang (Автор), Hiroshi Kurosaka (Автор), Masataka Kikuchi (Автор), Akihiro Nakaya (Автор), Paul A. Trainor (Автор), Takashi Yamashiro (Автор)
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• Опубликовано: The Company of Biologists, 2019-10-01T00:00:00Z.
• Предметы: article
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Cleft palate (CP) is one of the most common congenital craniofacial anomalies in humans and can be caused by either single or multiple genetic and environmental factor(s). With respect to environmental factors, excessive intake of vitamin A during early pregnancy is associated with increased inciden...