GWAS advancements to investigate disease associations and biological mechanisms

• Main Authors: Oluwaferanmi Omidiran (Author), Aashna Patel (Author), Sarah Usman (Author), Ishani Mhatre (Author), Habiba Abdelhalim (Author), William DeGroat (Author), Rishabh Narayanan (Author), Kritika Singh (Author), Dinesh Mendhe (Author), Zeeshan Ahmed (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Genome‐wide association studies (GWAS) have been instrumental in elucidating the genetic architecture of various traits and diseases. Despite the success of GWAS, inherent limitations such as identifying rare and ultra‐rare variants, the potential for spurious associations and pinpointing c...