Formulation, characterization, optimization, and in-vivo performance of febuxostat self-nano-emulsifying system loaded sublingual films
Febuxostat (FXS) is a potent antigout drug with poor water solubility and relative high first-pass effect leading to moderate oral bioavailability (<49%). This study aimed to increase FXS solubility and bioavailability by optimizing sublingual fast-dissolving films (SFs) containing a selected FXS...
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Main Authors: | , , , |
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Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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A1234.567 |
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