Indomethacin Decreases Arachidonic Acid Uptake in HCA-7 Human Colon Cancer Cells

• Main Authors: Takashi Orido (Author), Hiromichi Fujino (Author), Yuta Hasegawa (Author), Kaori Toyomura (Author), Tatsuo Kawashima (Author), Toshihiko Murayama (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the incidence of colorectal cancer. However, evidence is accumulating that NSAIDs have anti-cancer effects in addition to inhibiting cyclooxygenase (COX)-mediated prostanoid biosynthesis. We now show that indomethacin, a popular NSAID, significant...