Stimulation of TLR4 by recombinant HSP70 requires structural integrity of the HSP70 protein itself

Stimulation of TLR4 by recombinant HSP70 requires structural integrity of the HSP70 protein itself

<p>Abstract</p> <p>Background</p> <p>Toll-like receptor 4 (TLR4) is activated by bacterial endotoxin, a prototypical pathogen-associated molecular pattern (PAMP). It has been suggested that TLR4 can also be activated by damage-associated molecular pattern (DAMP) protein...

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Main Authors: Luong Michael (Author), Zhang Yanyu (Author), Chamberlain Tim (Author), Zhou Tianhui (Author), Wright Jill F (Author), Dower Ken (Author), Hall J Perry (Author)
Format: Book
Published: BMC, 2012-03-01T00:00:00Z.
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